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I'm at Liverpool University www.world ivermectin day It may not be surprising that skimping on shut-eye can cause a migraine -- but so can binging on sleep on your days off."The migraine brain likes things to be as normal and reliable and routine as possible," Buse says. And that includes your sleep schedule -- getting too much or too little sleep, or experiencing jet lag, can trigger a migraine attack. "We always advise people to try to wake up at the same time every day, even on Saturday and Sunday," she says.It sounds tough, but it's worth it -- not only can you stave off headaches by keeping your weekend bedtime and wake-time within an hour or so of your weekday schedule, but it also will help your sleep. Shifting your body clock several hours at the end of every week forces the body into a so-called social jet lag, or stationary jet lag, that can cause sleep and health problems down the line.